生物学最热门领域文章集(Cell系列)
以下文章是国外科学家最关心的文章系列,也意味着这些领域的研究是最热点的从这里我们可以看到免疫学,信号转导,Micro RNA,细胞因子,蛋白质组和基因组的研究,仍然是国际关注的焦点。同样我们与历年的影响因子期刊相印证,也得到类似结果。1. Nef-Mediated Suppression of T Cell Activation Was Lost in a Lentiviral Lineage that Gave Rise to HIV-1
Michael Schindler, Jan Münch, Olaf Kutsch, Hui Li, Mario L. Santiago, Frederic Bibollet-Ruche, Michaela C. Müller-Trutwin, Francis J. Novembre, Martine Peeters, Valerie Courgnaud, Elizabeth Bailes, Pierre Roques, Donald L. Sodora, Guido Silvestri, Paul M. Sharp, Beatrice H. Hahn and Frank Kirchhoff
[Summary] [Fulltext] [PDF] Jun 16, 2006 125 (6)
2. An Allosteric Mechanism for Activation of the Kinase Domain of Epidermal Growth Factor Receptor
Xuewu Zhang, Jodi Gureasko, Kui Shen, Philip A. Cole and John Kuriyan
[Summary] [Fulltext] [PDF] Jun 16, 2006 125 (6)
3. Phosphoinositide-Mediated Adaptor Recruitment Controls Toll-like Receptor Signaling
Jonathan C. Kagan and Ruslan Medzhitov
[Summary] [Fulltext] [PDF] Jun 02, 2006 125 (5)
4. A Conserved MST-FOXO Signaling Pathway Mediates Oxidative-Stress Responses and Extends Life Span
Maria K. Lehtinen, Zengqiang Yuan, Peter R. Boag, Yue Yang, Judit Villén, Esther B.E. Becker, Sara DiBacco, Núria de la Iglesia, Steven Gygi, T. Keith Blackwell and Azad Bonni
[Summary] [Fulltext] [PDF] Jun 02, 2006 125 (5)
5. Molecular Basis for the Recognition of Primary microRNAs by the Drosha-DGCR8 Complex
Jinju Han, Yoontae Lee, Kyu-Hyeon Yeom, Jin-Wu Nam, Inha Heo, Je-Keun Rhee, Sun Young Sohn, Yunje Cho, Byoung-Tak Zhang and V. Narry Kim
[Summary] [Fulltext] [PDF] Jun 02, 2006 125 (5)
6. PPM1A Functions as a Smad Phosphatase to Terminate TGF? Signaling
Xia Lin, Xueyan Duan, Yao-Yun Liang, Ying Su, Katharine H. Wrighton, Jianyin Long, Min Hu, Candi M. Davis, Jinrong Wang, F. Charles Brunicardi, Yigong Shi, Ye-Guang Chen, Anming Meng and Xin-Hua Feng
[Summary] [Fulltext] [PDF] Jun 02, 2006 125 (5)
7. p38 and a p38-Interacting Protein Are Critical for Downregulation of E-Cadherin during Mouse Gastrulation
Irene E. Zohn, Yingqiu Li, Edward Y. Skolnik, Kathryn V. Anderson, Jiahuai Han and Lee Niswander
[Summary] [Fulltext] [PDF] Jun 02, 2006 125 (5)
8. Striking it Rich by Data Mining
Jeffrey M. Rosen
[Summary] [Fulltext] [PDF] Aug 8, 2003 114 (3)
9. Tethering RITS to a Nascent Transcript Initiates RNAi- and Heterochromatin-Dependent Gene Silencing
Marc Bühler, André Verdel and Danesh Moazed
[Summary] [Fulltext] [PDF] Jun 02, 2006 125 (5)
10. Global Analysis of Protein Palmitoylation in Yeast
Amy F. Roth, Junmei Wan, Aaron O. Bailey, Beimeng Sun, Jason A. Kuchar, William N. Green, Brett S. Phinney, John R. Yates and Nicholas G. Davis
[Summary] [Fulltext] [PDF] Jun 02, 2006 125 (5)
11. Hematopoiesis Controlled by Distinct TIF1? and Smad4 Branches of the TGF? Pathway
Wei He, David C. Dorn, Hediye Erdjument-Bromage, Paul Tempst, Malcolm A.S. Moore and Joan Massagué
[Summary] [Fulltext] [PDF] Jun 02, 2006 125 (5)
12. A Role for TFIIIC Transcription Factor Complex in Genome Organization
Ken-ichi Noma, Hugh P. Cam, Richard J. Maraia and Shiv I.S. Grewal
[Summary] [Fulltext] [PDF] Jun 02, 2006 125 (5)
13. Growing Pains for NIH Grant Review
Laura Bonetta
[Summary] [Fulltext] [PDF] Jun 02, 2006 125 (5)
14. Control of Developmental Regulators by Polycomb in Human Embryonic Stem Cells
Tong Ihn Lee, Richard G. Jenner, Laurie A. Boyer, Matthew G. Guenther, Stuart S. Levine, Roshan M. Kumar, Brett Chevalier, Sarah E. Johnstone, Megan F. Cole, Kyo-ichi Isono, Haruhiko Koseki, Takuya Fuchikami, Kuniya Abe, Heather L. Murray, Jacob P. Zucker, Bingbing Yuan, George W. Bell, Elizabeth Herbolsheimer, Nancy M. Hannett, Kaiming Sun, Duncan T. Odom, Arie P. Otte, Thomas L. Volkert, David P. Bartel, Douglas A. Melton, David K. Gifford, Rudolf Jaenisch and Richard A. Young
[Summary] [Fulltext] [PDF] Apr 21, 2006 125 (2)
15. Live-Cell Imaging Reveals Replication of Individual Replicons in Eukaryotic Replication Factories
Etsushi Kitamura, J. Julian Blow and Tomoyuki U. Tanaka
[Summary] [Fulltext] [PDF] Jun 30, 2006 125 (7)
16. Spatiotemporal Feedback between Actomyosin and Focal-Adhesion Systems Optimizes Rapid Cell Migration
Stephanie L. Gupton and Clare M. Waterman-Storer
[Summary] [Fulltext] [PDF] Jun 30, 2006 125 (7)
17. SATB2 Is a Multifunctional Determinant of Craniofacial Patterning and Osteoblast Differentiation
Gergana Dobreva, Maria Chahrour, Marcel Dautzenberg, Laura Chirivella, Benoit Kanzler, Isabel Fari馻s, Gerard Karsenty and Rudolf Grosschedl
[Summary] [Fulltext] [PDF] Jun 02, 2006 125 (5)
18. Quality Control in Self/Nonself Discrimination
Thomas Boehm
[Summary] [Fulltext] [PDF] Jun 02, 2006 125 (5)
19. A Protein–Protein Interaction Network for Human Inherited Ataxias and Disorders of Purkinje Cell Degeneration
Janghoo Lim, Tong Hao, Chad Shaw, Akash J. Patel, Gábor Szabó, Jean-Fran鏾is Rual, C. Joseph Fisk, Ning Li, Alex Smolyar, David E. Hill, Albert-László Barabási, Marc Vidal and Huda Y. Zoghbi
[Summary] [Fulltext] [PDF] May 19, 2006 125 (4)
20. A Bivalent Chromatin Structure Marks Key Developmental Genes in Embryonic Stem Cells
Bradley E. Bernstein, Tarjei S. Mikkelsen, Xiaohui Xie, Michael Kamal, Dana J. Huebert, James Cuff, Ben Fry, Alex Meissner, Marius Wernig, Kathrin Plath, Rudolf Jaenisch, Alexandre Wagschal, Robert Feil, Stuart L. Schreiber and Eric S. Lander [url]http://forum.e2002.com/read.php?tid=84990[/url]
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