flash chromatography
各位前辈，小弟从事有机 合成不久，现在突然发现很多文献上的分离提纯用flash chromatography对我来说是全新的东西，于是上网搜看是什么东西，也好请教大家有没有这方面的经验，有这方面的专家更好，好给我们上上课，学习一下先进技术阿
我找到了一点相关的基础知识，和新手们一起学习：
Flash Chromatography
Chemistry 136
Flash chromatography, also known as medium pressure chromatography, was popularized
several years ago by Clark Still of Columbia University, as an alternative to slow and often
inefficient gravity-fed chromatography. Flash chromatography differs from the conventional
technique in two ways: first, slightly smaller silica gel particles (250-400 mesh) are used, and
second, due to restricted flow of solvent caused by the small gel particles, pressurized gas (ca. 10-
15 psi) is used to drive the solvent through the column of stationary phase. The net result is a rapid
(“over in a flash”) and high resolution chromatography.
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提取码3966829854064534 不错不错 [s:63] [s:63] 怎么各位同仁都没做过这方面的研究吗
那我得好好去做一些了， [s:62] 闪式柱层析，医药工业17（9）43-44，1986北京医科大学药学院教授凌仰之已经发表过了 主要是在展开剂的选择上要注意，要分离的点的Rf在0.3左右。分离很快的，一般1-2小时就能分离出来了。柱层析用的硅胶我现在用的是青岛产的。
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