Resveratrol in Health and Disease 全书下载
[hide=10][hide]Resveratrol in Health and Disease (Oxidative Stress and Disease)By Bharat B. Aggarwal (Editor), Shishir Shishodia (Editor)
Publisher: CRC
Number Of Pages: 712
Publication Date: 2005-11-01
ISBN / ASIN: 0849333717
Resveratrol is a phytochemical found naturally in red grapes, peanuts, and a number of other food plants with an ability to modulate multiple cellular targets that suggests suitability for the prevention and treatment of a range of diseases. The editors (both of the U. of Texas M. D. Anderson Cancer Center in Houston) of this volume present 27 papers that describe genes and cell signaling pathways affected by resveratrol and discuss preclinical studies on the potential of resveratrol in regards to cancer, cardiovascular diseases, and others. Specific topics include resveratrol as an antioxidant and as an antiproliferative agent for cancer, mechanisms of apoptosis by resveratrol, resveratrol as inhibitor of cell survival signal transduction, inhibition of cell cycle progression, molecular targets of resveratrol, angiogenesis inhibition, resveratrol modulation of gene expression, protective effects of resveratrol against ischemia-reperfusion, and other issues.
Contents
Chapter 1
Resveratrol: A Polyphenol for All Seasons . . . . . . . . . . . . . . . . . . . . . . . . . . 1
Shishir Shishodia and Bharat B. Aggarwal
Chapter 2
Sources and Chemistry of Resveratrol . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 17
Navindra P. Seeram, Vishal V. Kulkarni, and Subhash Padhye
Chapter 3
Resveratrol as an Antioxidant . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 33
Catalina Alarco磏 de la Lastra, Isabel Villegas, and
Antonio Ramo磏 Martı磏
Chapter 4
Resveratrol as an Antiproliferative Agent for Cancer . . . . . . . . . . . . . . 57
Paola Signorelli and Riccardo Ghidoni
Chapter 5
Mechanism of Apoptosis by Resveratrol . . . . . . . . . . . . . . . . . . . . . . . . . . . . 85
Shazib Pervaiz and Andrea Lisa Holme
Chapter 6
Resveratrol as Inhibitor of Cell Survival Signal Transduction. . . . . . . . 105
Simone Fulda and Klaus-Michael Debatin
Chapter 7
Resveratrol as Inhibitor of Cell Cycle Progression . . . . . . . . . . . . . . . . . . 119
Jen-Kun Lin
Chapter 8
Molecular Targets of Resveratrol: Implications to
Health and Disease Prevention . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 133
Catherine A. O’Brian and Feng Chu
Chapter 9
Resveratrol as an Angiogenesis Inhibitor . . . . . . . . . . . . . . . . . . . . . . . . . . 149
Ebba Bra˚kenhielm, Renhai Cao, and Yihai Cao
Chapter 10
Resveratrol Modulation of Gene Expression: The Role of
Transcription Factors . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 167
Fulvio Della Ragione, Valeria Cucciolla,
Adriana Borriello, and Vincenzo Zappia
Chapter 11
Modulation of Gene Expression by Resveratrol . . . . . . . . . . . . . . . . . . . . 193
Bhagavathi A. Narayanan and Narayanan K. Narayanan
Chapter 12
Resveratrol and Prostaglandin Biosynthesis . . . . . . . . . . . . . . . . . . . . . . . . 215
Lawrence M. Szewczuk and Trevor M. Penning
Chapter 13
Resveratrol as an Inhibitor of Carcinogenesis . . . . . . . . . . . . . . . . . . . . . . 233
John M. Pezzuto
Chapter 14
Resveratrol as an Antitumor Agent In Vivo . . . . . . . . . . . . . . . . . . . . . . . . 385
Francis Raul
Chapter 15
Resveratrol as a Sensitizer to Apoptosis-Inducing Stimuli . . . . . . . . . . 399
Ali R. Jazirehi and Benjamin Bonavida
Chapter 16
Resveratrol as a Radio-Protective Agent . . . . . . . . . . . . . . . . . . . . . . . . . . . . 423
Yogeshwer Shukla, Shannon Reagan-Shaw, and Nihal Ahmad
Chapter 17
Resveratrol as a Phytoestrogen . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 439
Barry D. Gehm and Anait S. Levenson
Chapter 18
Resveratrol as an Antibacterial Agent . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 465
Gail B. Mahady
Chapter 19
Resveratrol as an Antifungal Agent . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 475
Marielle Adrian and Philippe Jeandet
Chapter 20
Protective Effects of Resveratrol in Age-Related
Neurodegenerative Diseases and Gene Regulatory Action . . . . . . . . . . 499
Sofiyan Saleem, Abdullah Shafique Ahmad, and Sylvain Dore
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