恳求 妥曲珠利（Toltrazuril）药物的分析方法
请帮忙综述下妥曲珠利（Toltrazuril）药物的分析方法，或者告诉我在哪里可以找到分析方法。谢谢~~~！ 查过文献了吗？上CNKI和维普看看？
[url]http://www.google.cn/search?complete=1&hl=zh-CN&newwindow=1&client=aff-os-maxthon&hs=hDu&affdom=e2002.com&q=%E5%A6%A5%E6%9B%B2%E7%8F%A0%E5%88%A9Toltrazuril%E5%88%86%E6%9E%90%E6%96%B9%E6%B3%95&btnG=Google+%E6%90%9C%E7%B4%A2&meta=[/url] 不知楼主需要哪个方面的分析资料，检索了一下，有一篇关于该药品残留的检测方法：
1: J Chromatogr B Analyt Technol Biomed Life Sci. 2006 May 19;836(1-2):22-38.
Analysis of veterinary drug residues in shrimp: a multi-class method by liquid chromatography-quadrupole ion trap mass spectrometry.
Li H, Kijak PJ, Turnipseed SB, Cui W.
U.S. Food and Drug Administration, Center for Veterinary Medicine, Office of Research, Laurel, MD 20708, USA.
A liquid chromatography-mass spectrometry (LC-MS) method was developed to screen and confirm veterinary drug residues in raw shrimp meat. This method simultaneously monitors 18 drugs of different classes, including oxytetracycline (OTC), sulfonamides, quinolones, cationic dyes, and toltrazuril sulfone (TOLS). The homogenized shrimp meat is extracted with 5% trichloroacetic acid. The extract is further cleaned using polymer-based SPE. A 50 mm phenyl column separates the analytes, prior to analysis with an ion trap mass spectrometer interfaced with an atmospheric pressure chemical ionization source. This method is able to confirm oxytetracycline residues at 200 ng/g, toltrazuril sulfone at 50 ng/g, sulfaquinoxaline at 20 ng/g, and the other 15 drugs at 10 ng/g or lower levels. An estimate of the level of residues can also be made so that only confirmed samples above action levels will be sent for quantitation. The method is validated with both fortified and incurred samples, using multiple shrimp species as well. This multi-class method can provide a means to simultaneously monitor for a wide range of illegal drug residues in shrimp.
PMID: 16597519 [PubMed - indexed for MEDLINE]
另外这是个日本上市的兽药，有一篇关于这个药品的综述资料，包括该药品的理化性质，用法用量，药理，毒理资料（呵，比人用药还全）。如果有用请到下面链接下载
[url]http://www.isload.com.cn/store/6pa2jv34a7y2t/toltrazuril.pdf/downlaod[/url]
如果你是要做这个产品，想分析该产品的含量等一些数据，可以按普通化学品进行呀，看了一下结构，HPLC分析含量应该很容易操作！！
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