Voltage-Gated Ion Channels as Drug Targets
Voltage-Gated Ion Channels as Drug Targets (Methods and Principles in Medicinal Chemistry)By David J. Triggle, Murali Gopalakrishnan, David Rampe, Wei Zheng, Raimund Mannhold, Hugo Kubinyi, Gerd Folkers
* Publisher: Wiley-VCH
* Number Of Pages: 492
* Publication Date: 2006-04-17
* ISBN-10 / ASIN: 3527312587
* ISBN-13 / EAN: 9783527312580
* Binding: Hardcover
Book Description:
Edited by the most prominent person in the field and top researchers at US pharmaceutical companies, this is a unique resource for drug developers and physiologists seeking a molecular-level understanding of ion channel pharmacology.
After an introduction to the topic, the authors evaluate the structure and function of ion channels, as well as related drug interaction. A section on assay technologies is followed by a section each on calcium, sodium and potassium channels. Further chapters cover genetic and acquired channelopathies, before the book closes with a look at safety issues in ion channel drug development.
For medicinal and pharmaceutical chemists, biochemists, molecular biologists and those working in the pharmaceutical industry.
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