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qinjie 发表于 2008-4-29 18:16

BHT在保护冷冻精液中的作用

这篇文章是关于精液冷冻稀释液的配方比较的研究,BHT是一种抗氧化剂,结果使用BHT有良好的效果,这是讨论中的话,是说BHT是怎么起作用的,但具体的我看不懂,所以求助高人
In the light of the above-mentioned argument, it seems that BHT could interact synergistically with lipid vesicles in egg yolk to improve the functional competence of stored goat spermatozoa. During slow cooling of semen, the biophysical properties of BHT render it an organic soluble quasi-spherical hydrocarbon membrane perturbant molecule that can partition into the sperm plasma membrane compartments and lower the effective phase transition temperature of their lipid domains by as much as 10 C with a concurrent decrease in membrane lipid viscosity as well as a subsequent maintenance of membrane fluidity which is a prerequisite for proper sperm functions(Hammerstedt et al. 1976; Graham and Hammerstedt 1992).

xiaotianyuzi 发表于 2008-5-9 08:33

[font=楷体_GB2312][size=3][color=black]从上述的争论中可以看出:[color=red]BHT似乎可以和精子卵黄中的脂肪囊相互协同从而改善储藏精液的功能。[/color][/color][/size][/font]
[font=楷体_GB2312][size=3][color=black]主要原因如下:在精子的缓慢冷冻过程中,BHT特有的生物物理属性助其成为半球形的可溶性胞膜扰动分子,并分布到精子的胞膜中,在降低胞膜脂质粘性的同时,可以降低其有效相变温度达101度;当然在此过程中,胞膜的流动性依然得以保留,而这正是精子拥有正常功能的基础条件。[/color][/size][/font]

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