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sign 发表于 2008-10-4 16:25

J. Med. Chem. 2008,51(17-19)天然产物

J. Med. Chem. 2008,51(17-19)天然产物
原文选自 自然。手绘。化学
[url]http://phytomed.blogspot.com/2008/10/j-med-chem-20085117-19.html[/url]
1总结J. Med. Chem. 2008,51(17-19)上以天然产物或天然产物简单衍生物为研究对象的文章。
2按期定时更新
3引用本文请注明出处

1 Optimizing Natural Products by Biosynthetic Engineering: Discovery of Nonquinone Hsp90 Inhibitors
Ming-Qiang Zhang, Sabine Gaisser, Mohammad Nur-E-Alam, Lesley S. Sheehan, William A. Vousden, Nikolaos Gaitatzis, Gerrard Peck, Nigel J. Coates, Steven J. Moss, Markus Radzom, Teresa A. Foster, Rose M. Sheridan, Matthew A. Gregory, S. Mark Roe, Chrisostomos Prodromou, Laurence Pearl, Susan M. Boyd, Barrie Wilkinson, and Christine J. Martin
pp 5494 - 5497; (Letter) DOI: 10.1021/jm8006068

2 The Alkaloid Conessine and Analogues as Potent Histamine H3 Receptor Antagonists
Chen Zhao, Minghua Sun, Youssef L. Bennani, Sujatha M. Gopalakrishnan, David G. Witte, Thomas R. Miller, Kathleen M. Krueger, Kaitlin E. Browman, Christine Thiffault, Jill Wetter, Kennan C. Marsh, Arthur A. Hancock, Timothy A. Esbenshade, and Marlon D. Cowart
pp 5423 - 5430; (Article) DOI: 10.1021/jm8003625

3 Roscovitine-Derived, Dual-Specificity Inhibitors of Cyclin-Dependent Kinases and Casein Kinases 1
Nassima Oumata, Karima Bettayeb, Yoan Ferandin, Luc Demange, Angela Lopez-Giral, Marie-Lorène Goddard, Vassilios Myrianthopoulos, Emmanuel Mikros, Marc Flajolet, Paul Greengard, Laurent Meijer, and Hervé Galons
pp 5229 - 5242; (Article) DOI: 10.1021/jm800109e

4 Synthesis and Biological Evaluation of (−- and (+)-Debromoflustramine B and Its Analogues as Selective Butyrylcholinesterase Inhibitors
Ernesto Rivera-Becerril, Pedro Joseph-Nathan, Víctor M. Pérez-Álvarez, and Martha S. Morales-Ríos
pp 5271 - 5284; (Article) DOI: 10.1021/jm800277g

5 Modulating G-Protein Coupled Receptor/G-Protein Signal Transduction by Small Molecules Suggested by Virtual Screening
Christina M. Taylor, Yaniv Barda, Oleg G. Kisselev, and Garland R. Marshall
pp 5297 - 5303; (Article) DOI: 10.1021/jm800326q

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