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3#
发表于 2007-12-6 15:21
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Wu, G., Williams, H. D., Zamanian, M., Gibson, F. & Poole, R. K.
(1992). Isolation and characterisation of Escherichia coli mutants
affected in aerobic respiration : the cloning and nucleotide
sequence of ubiG. Identi甤ation of an S-adenosylmethioninebinding
motif in protein, RNA and small-molecule methyltransferases.
J Gen Microbiol 138, 2101±2112.
和我猜的一样,是一种低等生物的methyltransferase,
In eukaryotes, the first O-methylation step
is carried out by the Coq3 polypeptide, which catalyzes the transfer of a methyl group from
S-adenosylmethionine to 3,4-dihydroxy-5-polyprenylbenzoate. In Escherichia coli, 2-polyprenyl-6-
hydroxyphenol is the predicted substrate; however, the corresponding O-methyltransferase has not been
identified. The second O-methylation step in E. coli, the conversion of demethylubiquinone to ubiquinone,
is carried out by the UbiG methyltransferase, which is 40% identical in amino acid sequence with the
yeast Coq3 methyltransferase. |
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天涯苍苍日茫茫,风色萧萧海清凉!潮涨潮落何为是,待到功成再张扬! |
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